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This was completed in 1996. Even though Monsanto found no significant toxicity associated with its own product, in July 1997, the FDA's Center for Veterinary Medicine requested that manufacturers voluntarily reduce the maximum level for ethoxyquin by half, to 75 parts per million. While some pet food critics and veterinarians believe that ethoxyquin is a major cause of disease, skin problems, and infertility in dogs, others claim it is the safest, strongest, most stable preservative available for pet food. Ethoxyquin is approved for use in human food for preserving spices, such as cayenne and chili powder, at a level of 100 ppm -- but it would be very difficult to consume as much chili powder every day as a dog would eat dry food. Ethoxyquin has never been tested for safety in cats.
Some manufacturers have responded to consumer concern, and are now using "natural" preservatives such as Vitamin C (ascorbate), Vitamin E (mixed tocopherols), and oils of rosemary, clove, or other spices, to preserve the fats in their products. Other ingredients, however, may be individually preserved. Most fishmeal, and some prepared vitamin-mineral mixtures, contains chemical preservatives. This means that your companion animal may be eating food containing several types of preservatives. Federal law requires preservatives to be disclosed on the label; however, pet food companies only recently started to comply with this law.
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